Studies on the Himalayan yew Taxus wallichiana: Part VII - The taxoids and phenolic constituents of the roots of Taxus wallichiana t

نویسندگان

  • S K Chattopadhyay
  • M Kulshrestha
  • V Tripathi
  • G C Saha
  • R P Sharma
  • V K Mehta
چکیده

The systematic investigation on the roots of Taxus wallichiana has resulted in the isolation of nine taxoids-taxol 1 baccatin III 2, baccatin IV 3, taxusin 4, a C-14 oxygenated taxoid 5, I~-hydroxybaccatin 16, pentaacetoxy taxadiene 7, a dibenzoylated rearranged taxoid 8, 7-xylosyl-1 O-deacetyl-taxol C 9 and three phenolic compounds (-) seco-isolariciresinol 11, taxiresinol 12 and isotaxiresinol 13. The compounds have been characterized on the basis of their spectral characterist ics. The occurrence of taxoid 9 in the roots of the plant is quite significant. The distribution of the above compounds in other parts of the plant are also summarized.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A review of traditional use, phytoconstituents and biological activities of Himalayan yew, Taxus wallichiana.

Plants synthesize certain phytoconstituents for their protection, which, because they are not of primary need, are known as secondary metabolites. These secondary metabolites of plants, have often been found to have medicinal uses for human beings. One such gymnosperm having secondary metabolites of medicinal potential for humans is Taxus wallichiana (Himalayan yew). Besides being the source of...

متن کامل

Analysis of cell cultures of Taxus wallichiana using direct analysis in real-time mass spectrometric technique.

The applicability of a new mass spectrometric technique, DART (direct analysis in real time) has been studied in the analysis of the calli of Taxus wallichiana. The intact callus samples were directly analyzed by holding them in the gap between the DART source and mass spectrometer for measurements. Five C-14 oxygenated taxoids were characterized from the analysis of the calli of the Taxus wall...

متن کامل

An endophytic fungus efficiently producing paclitaxel isolated from Taxus wallichiana var. mairei

Paclitaxel is a medicinal ingredient with high anticancer activity and widely used in hospitals and clinics. In this study, we isolate endophytic fungi efficiently producing paclitaxel from yew for the purpose of paclitaxel manufacture.The bark of Taxus wallichiana var. mairei was surface sterilized and then inoculated in potato dextrose agar culture medium to isolate endophytic fungi. The pacl...

متن کامل

Development of microsatellite loci for Taxus wallichiana var. wallichiana (Taxaceae) and cross-amplification in Taxaceae.

Nine polymorphic microsatellite loci were isolated and characterized in Taxus wallichiana var. wallichiana, an endangered species in China. The number of alleles per locus ranged from 2 to 20. Observed and expected heterozygosities varied from 0.0260 to 0.5325 and 0.3603 to 0.9231, respectively. Positive cross-amplification of the 9 loci was observed in 2 other varieties of T. wallichiana and 4...

متن کامل

Seasonal Dynamics of Metabolites in Needles of Taxus wallichiana var. mairei.

Seasonal variations of the phytochemicals contents in needles of T. wallichiana var. mairei due to the effects of growth meteorological parameters were investigated in this study. The needles of T. wallichiana var. mairei were collected from different months and the contents of taxoids (paclitaxel, 10-deacetylbaccatin III (10-DAB), baccatin III, cephalomannine, 10-deacetyltaxol (10-DAT)), flavo...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012